Registration

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Register for the CAHRA Review Workshop here, including full details, a preliminary program, and all speakers.

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• Dates: 9:00 AM September 17th to 4:00 PM September 18th, 2026
• Venue: Rutherford Appleton Laboratory (RAL), Harwell in Oxfordshire, UK

Details

The CAHRA Review Workshop will host talks and discussion about “The Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms (CAHRA) Challenge” and the wider subject of interpreting and reconstructing the heterogeneity present in cryo-EM datasets. This will include talks…

• setting out the ground-truth behind each challenge dataset and analyzing their entries.
• from challenge winners/participants on their methodology.
• from experts addressing a range of topics, such as current limitations, potential opportunities from the use of HRAs, examples of their use in studies of cryo-EM datasets, and integrative approaches.

Talks at the workshop will be held in a hybrid manner. Please note that some speakers may request their presentation to be covered by a "No Publication Policy" similar to that used at Gordon Research Conferences; these talks will not be broadcast or recorded.

There will be ample time for in-person participants to discuss scoring metrics and challenge results, identify shortcomings of existing methods, brainstorm future metrics, explore integrative techniques and to discuss optimal representation, deposition, and reuse of heterogeneous structures.

The Workshop will be held in Diamond House at the Rutherford Appleton Laboratory (RAL), Harwell in Oxfordshire, UK from Thursday to Friday, September 17-18th, 2026. For in-person delegates, a limited numbers of rooms (free of charge, covered by DRIIMB sponsorship) are available at the Milton Hill House Hotel (MHH) on the nights of Wednesday and Thursday, September 16th and 17th. This accommodation includes evening meals, breakfast, and coach transport between RAL and MHH. These rooms will be allocated on a first-come, first-served basis upon registration. Lunch and coffee will be provided at RAL.

Speakers

• Peijun Zhang, University of Oxford, U.K.
• Sjors Scheres, MRC Laboratory of Molecular Biology, U.K.
• Mingxu Hu, Shenzhen Academy of Research and Translation, China
• David Haselbach, Research Institute of Molecular Pathology, Austria [EMBO Young Investigator Network talk]
• Hamish Todd, Altos Labs, U.S.
• Stephanie Wankowicz, Vanderbilt University, U.S.
• Others to be announced!